Synthesis of 2??Aminothiophenes on Ionic Liquid Phase Support using the Gewald Reaction

…, P Wei, H Huang, SQ Han, PK Ouyang

Index: Hu, Yi; Wei, Ping; Huang, He; Han, Shi-Qing; Ouyang, Ping-Kai Synthetic Communications, 2006 , vol. 36, # 11 p. 1543 - 1548

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Citation Number: 29

Abstract

Abstract The first report of the use of task??specific ionic liquid as soluble support for the Gewald synthesis of 2??aminothiophenes is reported in this article. This synthetic method is simple and efficient, and the products are obtained in good to excellent yields with high purities, without the need for chromatographic purification.