Bioorganic & Medicinal Chemistry Letters 2001-08-20

Caged Q-rhodamine dextran: a new photoactivated fluorescent tracer.

K R Gee, E S Weinberg, D J Kozlowski

Index: Bioorg. Med. Chem. Lett. 11 , 2181-2183, (2001)

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Abstract

An amine-reactive caged rhodamine was synthesized and conjugated to aminodextran. The resulting tracer was injected into a single cell zebrafish embryo, and a portion of the tracer was photolyzed in a single cell after development. The resulting fluorescent cell was imaged by fluorescence microscopy through a single round of cell division.