Synthetic communications

Mild, efficient, and selective cleavage of trityl ethers with antimony trichloride

Q Wu, Y Wang, W Chen, H Liu

Index: Wu, Qinpei; Wang, Yuan; Chen, Wei; Liu, Hua Synthetic Communications, 2006 , vol. 36, # 10 p. 1361 - 1366

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Citation Number: 12

Abstract

Abstract Selective detritylation is quite crucial in synthetic chemistry. A mild and efficient procedure for selective hydrolysis of trityl ethers in the presence of other frequently used hydroxy protecting groups: TBDPS, Bz, Bn, Ac and Ts with antimony trichloride was described and 5′??trityl uridine was detritylated smoothly too.