NeuroToxicology 2011-12-01

Fluazinam-induced apoptosis of SH-SY5Y cells is mediated by p53 and Bcl-2 family proteins

Jeong Eun Lee, Jin Sun Kang, In Chul Shin, Soo-Jin Lee, Dong-Hoon Hyun, Kyung Suk Lee, Hyun Chul Koh

Index: Neurotoxicology 32(6) , 702-10, (2011)

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Abstract

Highlights ► Fluazinam induced apoptotic cell death in SH-SY5Y cells. ► ROS is involved in fluazinam-mediated apoptotic cell death. ► Fluazinam-induced apoptosis is mediated by p53 and Bcl-2 family proteins.