Antimicrobial Agents and Chemotherapy 2007-12-01

BK Virus replication in vitro: limited effect of drugs interfering with viral uptake and intracellular transport.

Parmjeet Randhawa, Noush Afarin Farasati, Yuchen Huang

Index: Antimicrob. Agents Chemother. 51 , 4492-4, (2007)

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Abstract

BK virus is an important pathogen in kidney transplant recipients. In vitro studies demonstrated slight antiviral activity for chloroquine and nystatin. A sialic acid derivative, BTB11968, was identified as a lead compound for further development.