Abstract An instantaneous, selective and high-yielding halogenation process is reported. The method operates with imidazoles, pyrazoles, and indoles under benign reaction conditions. The developed process involves the use of N, N′-dihalo-5, 5- dimethylhydantoins (halo= chlorine, bromine, iodine) as halogenation reagents that are activated by catalytic quantities of a strong Brønsted acid. Moreover, the halogenation ...
