Organic Letters 2012-02-03

Cyclopropylmethyl palladium species from carbene migratory insertion: new routes to 1,3-butadienes.

Lei Zhou, Fei Ye, Yan Zhang, Jianbo Wang

Index: Org. Lett. 14(3) , 922-5, (2012)

Full Text: HTML

Abstract

Cyclopropylmethyl palladium species can be accessed by Pd-catalyzed reaction of either cyclopropyl N-tosylhydrazone with halide or N-tosylhydrazone with cyclopropyl halide. In both approaches migratory insertion of Pd carbene is the key process. These transformations constitute new approaches toward 1,3-butadiene derivatives.© 2012 American Chemical Society