Chemical Communications 2010-12-21

Copper-catalyzed decarboxylative cross-coupling of alkynyl carboxylic acids with aryl halides.

Dongbing Zhao, Chao Gao, Xiaoyu Su, Yunqing He, Jingsong You, Ying Xue

Index: Chem. Commun. (Camb.) 46(47) , 9049-51, (2010)

Full Text: HTML

Abstract

The copper-catalyzed decarboxylative reactions of alkynyl carboxylic acids with aryl halides were performed under relatively mild reaction conditions. Benzofurans could be further prepared smoothly by a one-pot domino protocol on the basis of decarboxylative cross-coupling of 2-iodophenol.