Synthesis and Evaluation of (Piperidinomethylene) bis (phosphonic acid) Derivatives as Anti-osteoporosis Agents.

三村三津夫， 林田三生， 野見山清， 池上悟…

Index: Chemical and Pharmaceutical Bulletin, , vol. 41, # 11 p. 1971 - 1986

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Citation Number: 20

Abstract

... Chemistry 4-Phenylpiperidine (1a) and 4-cyano-4-phenylpiperidine (1b) were treated with triethyl orthoformate in the presence of diethyl phosphite to afford tetraethyl ... H f : R"=N, Rº-H g : R'=CHCH, R*-H g : R"=CHCH, R*=H Chart 1 (Ç) 1993 Pharmaceutical Society of ... 1978 Vol. ...