Abstract In this paper we describe the chemoenzymatic synthesis of new enantiomerically enriched (R)-and (S)-1-(2-arylthiazol-4-yl) ethanols and their acetates by enzymatic enantioselective acetylation of the racemic alcohols rac-2a–d and by methanolysis of the corresponding racemic esters rac-3a–d mediated by lipase B from Candida antarctica (CaL- B) in non-aqueous media. In terms of stereoselectivity and activity, both procedures, ...