Chemical Communications 2010-06-21

Preparation of highly functionalized alkylzinc halides from alkyl bromides using Mg, ZnCl2 and LiCl.

Tobias D Blümke, Fabian M Piller, Paul Knochel

Index: Chem. Commun. (Camb.) 46(23) , 4082-4, (2010)

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Abstract

Alkyl bromides bearing various functional groups are smoothly converted to functionalized alkylzinc reagents by the direct insertion of magnesium in the presence of LiCl and ZnCl(2).