Tetrahedron letters

Zirconium tetrachloride as a mediator for ambient temperature ortho-fries rearrangements

DC Harrowven, RF Dainty

Index: Harrowven, David C.; Dainty, Richard F. Tetrahedron Letters, 1996 , vol. 37, # 42 p. 7659 - 7660

Full Text: HTML

Citation Number: 51

Abstract

Zirconium tetrachloride has been found to be an excellent mediator of the Fries reaction. Rearrangements occur at ambient temperature and are highly selective; giving the acetophenone derived from acetyl migration to the sterically least encumbered adjacent carbon.