Organic Letters 2010-09-17

Synthesis of sulfuric macrocycles and a rotaxane through thiol-yne click and dithiol coupling reactions.

Weidong Zhou, Haiyan Zheng, Yongjun Li, Huibiao Liu, Yuliang Li

Index: Org. Lett. 12(18) , 4078-81, (2010)

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Abstract

A macrocycle and a rotaxane were constructed by virtue of the thiol-yne click reaction under the irradiation of light in high yield, which can proceed at ambient temperature and humidity under an air atmosphere. Two disulfide macrocycles were synthesized through a simple dithiol coupling reaction, which exhibited high stability and a weak assembly interaction with a dialkylammonium ion.