Synthesis

Optically pure (S)-6, 7-dimethoxy-1, 2, 3, 4-tetrahydro-3-isoquinolinecarboxylic acid and asymmetric hydrogenation studies related to its preparation

NJ O'reilly, WS Derwin, HC Lin

Index: Synthesis, , # 7 p. 550 - 556

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Citation Number: 18

Abstract

... 1° Of particular interest to us was (S)-6,7-dimethoxy- 1,2,3,4-tetrahydro-3 ... used, route to (Z )-2-acylamino-3- (3,4-dimethoxyphenyl)-2-propenoates is the classical Ehrlenmeyer azlactone synthesis. ... a- Sub- R' R L*“ Solvent Time YieldI7 eel' strate (11) (%) (0/0) 3b Me Ph P THF 5 ...