Boronate linker for 'traceless' solid-phase synthesis

C Pourbaix, F Carreaux, B Carboni…

Index: Pourbaix, Christelle; Carreaux, Francois; Carboni, Bertrand; Deleuze, Herve Chemical Communications, 2000 , # 14 p. 1275 - 1276

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Citation Number: 14

Abstract

The combinatorial library approach is increasingly used for the discovery and development of new drugs, catalysts and materials. 1 Most of the organic chemical libraries reported to date have been constructed using solid-phase methods. A key aspect of these strategies is the linkage element, which acts as a tether to the polymeric support material. Typically, linkage to the polymeric support is based on a protecting group. However, after cleavage from the support, the ...