Journal of Microbiological Methods 2011-10-01

Diagnostic utility of combination of inducer and inhibitor based assay in detection of Pseudomonas aeruginosa producing AmpC β-lactamase.

Supriya Upadhyay, Malay Ranjan Sen, Amitabha Bhattacharjee, Pradyot Prakash, Ram Chandra Bajpai, Shampa Anupurba

Index: J. Microbiol. Methods 87(1) , 116-8, (2011)

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Abstract

The diagnostic utility of inducer and inhibitor based assays among 214 AmpC positive isolates of Pseudomonas aeruginosa were evaluated. Of different methods, combination of ceftazidime-imipenem antagonism and boronic acid inhibition tests came up with maximum sensitivity (76%) and specificity (100%). This combination showed reliability for both inducible and non-inducible AmpC producers.Copyright © 2011 Elsevier B.V. All rights reserved.