Compte rendu des seances de la Societe de Biologie, Paris. Paris 1982-01-01

[Inductive effects of enzymes of salicylic acid derivatives].

H Goudonnet, J Mounié, K Bereksi-Reguig, R Truchot

Index: C. R. Seances. Soc. Biol. Fil. 176(5) , 707-15, (1982)

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Abstract

In the series of salicylic acids derivatives investigated 3,5-DIS has a large inductive effect of enzymes with respect to the metabolism of xenobiotics: rise in the rate of Cyt. P 450; increase of ethoxycoumarin deethylase, bilirubin glucuronosyl transferase and benzphetamine-N-demethylase activities. This effect is comparable with that of phenobarbital.