Organic Letters 2007-07-05

An efficient synthesis of nitroalkenes by alkene cross metathesis: facile access to small ring systems.

Graham P Marsh, Philip J Parsons, Clive McCarthy, Xavier G Corniquet

Index: Org. Lett. 9 , 2613, (2007)

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Abstract

A synthesis of highly functionalized nitroalkenes is reported that utilizes a cross metathesis (CM) reaction between simple aliphatic nitro compounds and a range of substituted alkenes. This chemistry offers a simple and attractive route to nitroalkenes that would otherwise be difficult to prepare, and that have a very useful application as precursors to a variety of heterocyclic entities.