Organic Letters 2007-08-16

A concise total synthesis of melithiazole C.

Julian Gebauer, Stellios Arseniyadis, Janine Cossy

Index: Org. Lett. 9 , 3425, (2007)

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Abstract

A short and convergent synthesis of the myxobacterial antibiotic melithiazole C is described featuring a highly E-selective cross-metathesis as the key step.