Journal of Natural Products 2010-08-27

Lactones and quinones from the tubers of Sinningia aggregata.

Maria Helena Verdan, Andersson Barison, Eduardo Lemos de Sá, Marcos J Salvador, Clarisse B Poliquesi, Marcos N Eberlin, Maria Elida A Stefanello

Index: J. Nat. Prod. 73(8) , 1434-7, (2010)

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Abstract

Three new aromatic epsilon-lactones, aggregatins A (1), B (2), and C (3), a new naphthoquinone derivative, aggregatin D (4), and three known anthraquinones, 2-methylanthraquinone, 7-methoxy-2-methylanthraquinone, and 7-hydroxy-2-methylanthraquinone, were isolated from the tubers of Sinningia aggregata (Gesneriaceae). Compounds 1 and 4 and the anthraquinones showed marginal antimicrobial activity.