Yao xue xue bao = Acta pharmaceutica Sinica 2010-03-01

[Two new sesquiterpene lactones from the pericarp of Illicium macranthum].

Hai-juan Ma, Chang-hua Ma, Jian-mei Huang

Index: Yao Xue Xue Bao 45(3) , 330-3, (2010)

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Abstract

Silica gel column chromatography was used for the isolation and purification of the chemical constituents of the pericarp of Illicium macranthum. From dichloromethane-EtOAc (1:1) fraction and EtOAc fraction of the methanol extracts, eleven compounds were identified on the basis of chemical and spectral data. Two new compounds were elucidated to be 6-deoxyneomajucin (1) and 2-oxo-6-deoxyneomajucin (2), along with nine known compounds 6-deoxypseudoanisatin (3), pseudoanisatin (4), anisatin (5), pseudomajucin (6), protocatecheuic acid (7), shikimic acid (8), shikimic acid methylester (9), beta-sitosterol (10) and daucosterol (11). Compounds 1 and 2 are new majucin-type sesquiterpene lactones.