Brain Research Bulletin 2011-01-01

Chemical stimulation of the ST36 acupoint reduces both formalin-induced nociceptive behaviors and spinal astrocyte activation via spinal alpha-2 adrenoceptors

Suk-Yun Kang, Chi-Young Kim, Dae-Hyun Roh, Seo-Yeon Yoon, Ji-Ho Park, Hye-Jung Lee, Alvin J. Beitz, Jang-Hern Lee

Index: Brain Res. Bull. 86(5-6) , 412-21, (2011)

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Abstract

Highlights ► DBV's anti-nociceptive effect involves suppression of spinal astrocyte activation. ► DBV-induced astrocyte inhibition is mediated by spinal alpha-2A and alpha-2C adrenoceptors. ► Astrocyte modulation by DBV is potentiated by i.t. administration of fluorocitrate.