Enantioselective Access to Chiral Drugs by using Asymmetric Hydrogenation Catalyzed by Rh (P OP) Complexes

…, H Fernández??Pérez, A Vidal??Ferran

Index: Etayo, Pablo; Nunez-Rico, Jose Luis; Fernandez-Perez, Hector; Vidal-Ferran, Anton Chemistry - A European Journal, 2011 , vol. 17, # 50 p. 13978 - 13982

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Citation Number: 19

Abstract

The synthetic challenges arising from the high degree of enantiopurity required in life- science products have fuelled the development and industrial application of asymmetric catalysis. Indeed, asymmetric catalysis should be considered, a priori, the best method to introduce chirality into any production process.[1] Since the very early days of asymmetric catalysis, intensive research activities on asymmetric hydrogenation have been followed ...