e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Electron transfer in reactions of ketones with organolithium reagents. A carbon-14 kinetic isotope effect probe
H Yamataka, N Fujimura, Y Kawafuji…
Index: Yamataka, Hiroshi; Fujimura, Naoya; Kawafuji, Yukie; Hanafusa, Terukiyo Journal of the American Chemical Society, 1987 , vol. 109, # 14 p. 4305 - 4308
Abstract: Kinetic isotope effects have been determined for reactions of ketones labeled with carbon-14 at the carbonyl carbon with MeLi and Me2CuLi in diethyl ether at 0 OC. Observed isotope effects were as follows:(C6H5)* C= 0+ MeLi," k/I4k= 1.000 f 0.002;(C6H5) &= 0+ Me2CuLi, 1.029 & 0.005; 2, 4, 6-Me&H2COC, &5+ MeLi, 1.023 f 0.004. The relative reactivities of ortho-, meta-, and para-substituted benzophenones with these reagents ...
