One??Pot Synthesis of Unsymmetrical Benzils by Oxidative Coupling Using Selenium Dioxide and p??Toluenesulfonic Acid Monohydrate

M Rohman, I Kharkongor, M Rajbangshi…

Index: Rohman, Md. Rumum; Kharkongor, Icydora; Rajbangshi, Mantu; Mecadon, Hormi; Laloo, Badaker M.; Sahu, Priti R.; Kharbangar, Iadeishisha; Myrboh, Bekington European Journal of Organic Chemistry, 2012 , # 2 p. 320 - 328

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Citation Number: 10

Abstract

Abstract The oxidative coupling of the α-carbon atom of aromatic ketones with unactivated arenes in the presence of selenium dioxide and p-toluenesulfonic acid monohydrate is described. A number of unsymmetrical benzils have been prepared in good yields (38–75%) with high regioselectivity. The generality and functional tolerance of this new protocol is demonstrated. The mechanistic pathway for the oxidative coupling reaction is also ...