Chemical Communications 2005-02-07

gem-Difluorination of 2,2-diaryl-1,3-dithiolanes by Selectfluor and pyridinium polyhydrogen fluoride.

V Prakash Reddy, Ramesh Alleti, Meher K Perambuduru, Urs Welz-Biermann, Herwig Buchholz, G K Surya Prakash

Index: Chem. Commun. (Camb.) , 654, (2005)

Full Text: HTML

Abstract

2,2-diaryl-1,3-dithiolanes, readily obtainable from diaryl ketones, were transformed into the corresponding gem-difluoro compounds using a novel reagent combination involving Selectfluor and pyridinium polyhydrogen fluoride (PPHF) under mild conditions in moderate to good yields.