Tetrahedron letters

A short synthesis of oxazolidinone derivatives linezolid and eperezolid: a new class of antibacterials

BB Lohray, S Baskaran, BS Rao, BY Reddy, IN Rao

Index: Lohray, Braj B.; Baskaran, Sundarababu; Rao, B. Srinivasa; Reddy, B. Yadi; Rao, I. Nageswara Tetrahedron Letters, 1999 , vol. 40, # 26 p. 4855 - 4856

Full Text: HTML

Citation Number: 95

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Oxazolidinone derivatives such as Linezolid and Eperazolid, which are a new class of antibacterials, have been synthesized from 1,2,5,6-dianhydro-3,4-isopropylidine-D-mannitol in good yield. ... An atom economical approach has been used for the synthesis of ...

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(R)-3-(3-fluoro-4-(4-(2-hydroxyacetyl)piperazin-1-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one Structure

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(R)-3-(3-fluoro...

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Eperezolid Structure

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Eperezolid Structure

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Eperezolid

(5R,5'R)-5,5'-((4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl)bis(3-(3-fluoro-4-(4-(2-hydroxyacetyl)piperazin-1-yl)phenyl)oxazolidin-2-one) Structure

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(5R,5'R)-5,5'-(...

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