Amino Acids 2004-12-01

Hexafluoroacetone as protecting and activating reagent: site-selective functionalization of iminodiacetic acid.

T Rühl, C Böttcher, L Hennig, K Burger

Index: Amino Acids 27(3-4) , 285-90, (2004)

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Abstract

Hexafluoroacetone was applied as a bidentate protecting and activating agent for the syntheses of RGD-peptide mimetics starting from iminodiacetic acid in solution and on solid phase.