Journal of Organic Chemistry 2006-05-12

Microwave-assisted preparation of fused bicyclic heteroaryl boronates: application in one-pot Suzuki couplings.

Erin F DiMauro, Jason R Vitullo

Index: J. Org. Chem. 71 , 3959, (2006)

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Abstract

The rapid and efficient synthesis of various disubstituted 5,6-fused heterocycles using a microwave-assisted one-pot cyclization-Suzuki coupling approach is described. This work highlights the tolerance of the boronic ester functional group to a variety of reaction conditions and the utility of functionalized boronates as penultimate intermediates in the synthesis of diverse compound libraries.