A series of new nitrogen heterocyclic compounds containing sulfur–ether (8a–8f) and Schiff-base (9a–9q) functionalities were synthesized by the reaction of the pharmaceutical lead compound containing both benzimidazole and 1,2,4-triazole rings. The compounds were characterized by 1 H NMR, 13 C NMR, FT-IR, HR-MS, and ESI-MS. ... [Supplementary materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfer, and Silicon and ...