Scandinavian journal of dental research 1988-10-01

Effect of copper fluoride and copper sulfate on dental plaque, Streptococcus mutans and caries in hamsters.

M Maltz, C G Emilson

Index: Scand. J. Dent. Res. 96(5) , 390-2, (1988)

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Abstract

Topical applications of 10 mM CuF2, 10 mM CuSO4, or 20 mM NaF solutions were performed twice a day in hamsters infected with S. mutans and maintained on a high sucrose diet. Animals receiving the copper compounds exhibited lower plaque scores than control animals or animals treated with the NaF solution. The group receiving the CuF2 solution showed a lower number of S. mutans and a higher caries reduction than the groups treated with NaF or the non-fluoride compound CuSO4.