Science 2014-05-01

Comment on "Revealing nature's cellulase diversity: the digestion mechanism of Caldicellulosiruptor bescii CelA".

AlexanderV Gusakov

Index: Science 344(6184) , 578, (2014)

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Abstract

Brunecky et al. (Reports, 20 December 2013, p. 1513) compared the cellulolytic activity of bacterial multimodular cellulase CelA with fungal Cel7A (cellobiohydrolase I from Trichoderma reesei). If more active Cel7A from another fungus were used as a reference enzyme under optimal conditions with _-glucosidase added, the reported difference between bacterial and fungal enzymes would be less dramatic.