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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Structure-activity relationship of small-sized HIV protease inhibitors containing allophenylnorstatine

T Mimoto, R Kato, H Takaku, S Nojima…

Index: Journal of Medicinal Chemistry, , vol. 42, # 10 p. 1789 - 1802

Full Text: HTML

Citation Number: 92

Abstract

... Journal of ... Pharmaceuticals & Biotechnology Laboratory, Japan Energy Corporation, Toda-shi, Saitama 335-8502, Japan, and Department of Medicinal Chemistry, Kyoto Pharmaceutical University, Yamashina-ku, Kyoto 607-8414, Japan. J. Med. Chem. ...

 Related Synthetic Route
L-penicillamine Structure

1113-41-3

L-penicillamine

~%

(R)-3-(tert-Butoxycarbonyl)-5,5-dimethylthiazolidine-4-carboxylic acid Structure

117918-23-7

(R)-3-(tert-But...

2,6-Dimethylbenzoic acid Structure

632-46-2

2,6-Dimethylben...

methyl iodide Structure

74-88-4

methyl iodide

~%

Methyl 2,6-dimethylbenzoate Structure

14920-81-1

Methyl 2,6-dime...

2-(2,6-di-methylbenzyl)isoindoline-1,3-dione Structure

130403-21-3

2-(2,6-di-methy...

~%

1-(2,6-Dimethylphenyl)methanamine Structure

74788-82-2

1-(2,6-Dimethyl...

2,6-Dimethylbenzoic acid Structure

632-46-2

2,6-Dimethylben...

~%

1-(2,6-Dimethylphenyl)methanamine Structure

74788-82-2

1-(2,6-Dimethyl...

2,6-Dimethyl benzylchloride Structure

5402-60-8

2,6-Dimethyl be...

~%

1-(2,6-Dimethylphenyl)methanamine Structure

74788-82-2

1-(2,6-Dimethyl...

Methyl 2,6-dimethylbenzoate Structure

14920-81-1

Methyl 2,6-dime...

~%

1-(2,6-Dimethylphenyl)methanamine Structure

74788-82-2

1-(2,6-Dimethyl...

(2,6-Dimethylphenyl)methanol Structure

62285-58-9

(2,6-Dimethylph...

~%

1-(2,6-Dimethylphenyl)methanamine Structure

74788-82-2

1-(2,6-Dimethyl...

Methyl (3-methylphenoxy)acetate Structure

63051-20-7

Methyl (3-methy...

~%

(3-Methylphenoxy)acetic acid Structure

1643-15-8

(3-Methylphenox...

m-Cresol Structure

108-39-4

m-Cresol

~%

(3-Methylphenoxy)acetic acid Structure

1643-15-8

(3-Methylphenox...

methyl 2-(2,6-dimethylphenoxy)acetate Structure

38930-22-2

methyl 2-(2,6-d...

~%

2,6-Dimethylphenoxyacetic acid Structure

13335-71-2

2,6-Dimethylphe...

2,6-Dimethylbenzoic acid Structure

632-46-2

2,6-Dimethylben...

~%

2,6-Dimethyl benzylchloride Structure

5402-60-8

2,6-Dimethyl be...

Methyl 2,6-dimethylbenzoate Structure

14920-81-1

Methyl 2,6-dime...

~%

2,6-Dimethyl benzylchloride Structure

5402-60-8

2,6-Dimethyl be...

2-(2-methylphenoxy)methylethanoate Structure

2989-17-5

2-(2-methylphen...

~%

(2-Methylphenoxy)acetic acid Structure

1878-49-5

(2-Methylphenox...

o-cresol Structure

95-48-7

o-cresol

~%

(2-Methylphenoxy)acetic acid Structure

1878-49-5

(2-Methylphenox...

Related Articles: More...
Design and synthesis of highly potent HIV protease inhibitor...

[Lu, Zhijian; Raghavan, Subharekha; Bohn, Joann; Charest, Mark; Stahlhut, Mark W.; Rutkowski, Carrie A.; Simcoe, Amy L.; Olsen, David B.; Schleif, William A.; Carella, Anthony; Gabryelski, Lori; Jin, Lixia; Lin, Jiunn H.; Emini, Emilio; Chapman, Kevin; Tata, James R. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 10 p. 1821 - 1824]
A concise synthesis of (2S, 3S)-BocAHPBA and (R)-BocDMTA, ch...

[Ikunaka, Masaya; Matsumoto, Jun; Nishimoto, Yukifumi Tetrahedron Asymmetry, 2002 , vol. 13, # 11 p. 1201 - 1208]
A concise synthesis of (2S, 3S)-BocAHPBA and (R)-BocDMTA, ch...

[Tetrahedron Asymmetry, , vol. 13, # 11 p. 1201 - 1208]
A concise synthesis of (2S, 3S)-BocAHPBA and (R)-BocDMTA, ch...

[Tetrahedron Asymmetry, , vol. 13, # 11 p. 1201 - 1208]

Detail Synthetic Route


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