Ligustrazine Derivatives. Part 4: Design, Synthesis, and Biological Evaluation of Novel Ligustrazine??based Stilbene Derivatives as Potential Cardiovascular Agents

L Deng, X Guo, L Zhai, Y Song, H Chen…

Index: Chemical Biology and Drug Design, , vol. 79, # 5 p. 731 - 739

Full Text: HTML

Citation Number: 14

Abstract

... Chemical Biology & Drug Design, 79: 731–739. ... was introduced to stilbene by replacement of the phenyl group, according to the bioisosteric replacement principle of medicinal chemistry. ... Chemical shifts are expressed in δ units with tetramethylsilane (TMS) as internal reference. ...