Structure–activity relationships of 1, 4-dihydropyridines that act as enhancers of the vanilloid receptor 1 (TRPV1)

EJ Roh, JM Keller, Z Olah, MJ Iadarola…

Index: Bioorganic and Medicinal Chemistry, , vol. 16, # 20 p. 9349 - 9358

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Citation Number: 29

Abstract

... Bioorganic & Medicinal Chemistry. ... a Molecular Recognition Section, Laboratory of Bioorganic Chemistry, National Institute of ... such as capsaicin activate ion flux through the TRPV1 channel, a heat- and ligand-gated cation channel that transduces painful chemical or thermal ...