Steroids

Phenylalanine 93 of the human UGT1A10 plays a major role in the interactions of the enzyme with estrogens

C Höglund, N Sneitz, A Radominska-Pandya…

Index: Steroids, , vol. 76, # 13 p. 1465 - 1473

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Citation Number: 10

Abstract

... this site in more detail, using site directed mutagenesis, activity analyses of steroids, coumarins and ... in duplicates (at most 15% difference between duplicates), in a final volume of 100 μl. ... in the F93A mutant and, strikingly, very high activity toward this synthetic steroid by F93G ...