Cytobios 1989-01-01

Effect of hyperthermia on lymphocyte plasma membrane. 3 electrolyte spin labels permeability.

M Koter

Index: Cytobios. 58(234-35) , 165-70, (1989)

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Abstract

The effect of elevated temperatures on the transport of electrolyte spin labels anionic c-TEMPIR and cationic TEMPO-choline character across the porcine lymphocyte plasma membrane was investigated. Breaks in the Arrhenius plot for permeability of both spin-labels occurred at 42 to 43 degrees C. TEMPO-choline and c-TEMPIR transport are probably critical targets in hyperthermic cell killing.