Cell Biology International 2000-01-01

Catalase activity in human erythrocytes: effect of phenoxyherbicides and their metabolites.

B Bukowska, A Chajdys, W Duda, P Duchnowicz

Index: Cell Biol. Int. 24(10) , 705-11, (2000)

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Abstract

The effects of exposure to different concentrations of phenoxyherbicides and their metabolites were studied in human erythrocytes, with particular attention to catalase (CAT-EC. 1.11.1. 6- hydrogen peroxide: hydrogen peroxide oxidoreductase). 4-chloro-2-methylphenoxyacetic acid (MCPA), 2,4-dimethylphenol (2, 4-DMP) and 2,4-dichlorophenoxyacetic acid (2,4-D) did not affect CAT activity, but 2,4-dichlorophenol (2,4-DCP) and 2,4,5-trichlorophenol (2,4,5-TCP) decrease its activity, the latter being the more inhibitory.Copyright 2000 Academic Press.