Phytotherapy Research 2008-06-01

Effects of cuminaldehyde on melanoma cells.

Teruhiko Nitoda, Maria D Fan, Isao Kubo

Index: Phytother Res. 22(6) , 809-13, (2008)

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Abstract

Cuminaldehyde (4-isopropylbenzaldehyde) suppressed melanin formation in cultured murine B16-F10 melanoma cells in a dose-dependent decrease up to 0.25 mm without affecting cell growth. Approximately 30% suppression in melanin production resulted when the cells were cultured with 0.25 mm of cuminaldehyde. This activity was not noticeable with cultured human A375 melanoma cells.Copyright (c) 2008 John Wiley & Sons, Ltd.