e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Liebigs Annalen der Chemie

Anwendungen der Phasentransfer??katalyse, 14. Darstellung von Alkinen aus Alkylhalogeniden mit festem Kalium??tert??butylat und Kronenether

EV Dehmlow, M Lissel

Index: Dehmlow, Eckehard V.; Lissel, Manfred Liebigs Annalen der Chemie, 1980 , # 1 p. 1 - 13

Full Text: HTML

Citation Number: 29

Abstract

Abstract Präparativ einfach und milde verläuft die HX-Eliminierung mit festem Kalium-tert- butylat in Petrolether bei Gegenwart katalytischer Mengen [18] Krone-6. 1, 2-Dihalogenide (aus Alkenen) sowie 1, 1-Dihalogenide (aus Aldehyden) liefern 1-Alkine, mittelständig geminale Dihalogenide (aus symmetrischen Ketonen) liefern mittelständige Alkine in sehr guten Ausbeuten. 2, 2-Dihalogenide (aus Methylketonen) geben nur dann völlig ...

2-chloroundec-1-ene Structure

2-chloroundec-1-ene

~18%

1-Undecyne Structure

undec-2-yne Structure

undeca-1,2-diene Structure

undeca-1,2-diene

(E)-2-Chlor-2-undecen Structure

(E)-2-Chlor-2-u...

~70%

1-Undecyne Structure

undec-2-yne Structure

undeca-1,2-diene Structure

undeca-1,2-diene

2,2-dichloro-undecane Structure

2,2-dichloro-un...

~%

1-Undecyne Structure

undec-2-yne Structure

undeca-1,2-diene Structure

undeca-1,2-diene

2-chloroundec-1-ene Structure

2-chloroundec-1-ene

~8%

1-Undecyne Structure

undec-2-yne Structure

undeca-1,2-diene Structure

undeca-1,2-diene

(E)-2-Chlor-2-undecen Structure

(E)-2-Chlor-2-u...

~6%

1-Undecyne Structure

undec-2-yne Structure

undeca-1,2-diene Structure

undeca-1,2-diene

2,2-dichloro-undecane Structure

2,2-dichloro-un...

~%

1-Undecyne Structure

undec-2-yne Structure

undeca-1,2-diene Structure

undeca-1,2-diene

Oct-1-yne Structure

~94%

2-Octyne Structure

2,2-Dichlorooctane Structure

2,2-Dichlorooctane

~14%

2-Octyne Structure

Oct-1-yne Structure

1-Pentylallene Structure

2-Octanone Structure

~%

2-Octyne Structure

1,2-DBROMOHEXANE Structure

1,2-DBROMOHEXANE

~97%

Hex-1-yne Structure

2-Bromo-1-hexene Structure

2-Bromo-1-hexene

~93%

Hex-1-yne Structure

(Z)-1-bromohex-1-ene Structure

(Z)-1-bromohex-1-ene

~93%

Hex-1-yne Structure

1-Hexene, 1-bromo-,(1E)- Structure

1-Hexene, 1-bro...

~95%

Hex-1-yne Structure

1,2-DBROMOHEXANE Structure

1,2-DBROMOHEXANE

~8%

2-Bromo-1-hexene Structure

2-Bromo-1-hexene

(Z)-1-bromohex-1-ene Structure

(Z)-1-bromohex-1-ene

1-Hexene, 1-bromo-,(1E)- Structure

1-Hexene, 1-bro...

Detail

(E)-1-Chlor-2-ethoxyethen Structure

(E)-1-Chlor-2-e...

~75%

Ethoxyethyne Structure

3,3-dichloropentane Structure

3,3-dichloropentane

~81%

Pent-2-yne Structure

1,2-dibromodecane Structure

1,2-dibromodecane

~85%

dec-1-yne Structure

(Z)-1-chloro-2-ethoxyethene Structure

(Z)-1-chloro-2-...

~86%

Ethoxyethyne Structure

(3,3-Dichloropropyl)benzene Structure

(3,3-Dichloropr...

~28%

phenylpropyne Structure

Benzene, (3-chloroallyl)- Structure

Benzene, (3-chl...

(+/-)-1,2-dibromooctane Structure

(+/-)-1,2-dibro...

~0%

Oct-1-yne Structure

2-Bromo-1-octene Structure

2-Bromo-1-octene

(Z)-1-bromo-oct-1-ene Structure

(Z)-1-bromo-oct...

Detail

2-Bromo-1-octene Structure

2-Bromo-1-octene

~89%

Oct-1-yne Structure

3-acetoxy-3,4,4-trimethyl-pentan-2-one Structure

3-acetoxy-3,4,4...

~91%

Oct-1-yne Structure

1,2-Dichlorooctane Structure

1,2-Dichlorooctane

~85%

Oct-1-yne Structure

(+/-)-1,2-dibromooctane Structure

(+/-)-1,2-dibro...

~6%

Oct-1-yne Structure

2-Bromo-1-octene Structure

2-Bromo-1-octene

(Z)-1-bromo-oct-1-ene Structure

(Z)-1-bromo-oct...

Detail

2,2-Dichloro-3-methylbutane Structure

2,2-Dichloro-3-...

~77%

3-Methyl-1-butyne Structure

3-Methyl-1-butyne

1,2-DBROMOHEXANE Structure

1,2-DBROMOHEXANE

~0%

2-Bromo-1-hexene Structure

2-Bromo-1-hexene

(Z)-1-bromohex-1-ene Structure

(Z)-1-bromohex-1-ene

1-Hexene, 1-bromo-,(1E)- Structure

1-Hexene, 1-bro...

Detail

Benzenepropanoic acid, a,b-dibromo-, ethyl ester Structure

Benzenepropanoi...

~79%

Ethyl 3-phenyl-2-propynoate Structure

Ethyl 3-phenyl-...

Butane,1,2-dibromo-3,3-dimethyl- Structure

Butane,1,2-dibr...

~90%

3,3-Dimethyl-1-Butyne Structure

3,3-Dimethyl-1-...

2,2-Dichloro-3,3-dimethylbutane Structure

2,2-Dichloro-3,...

~96%

3,3-Dimethyl-1-Butyne Structure

3,3-Dimethyl-1-...

2-Octanone Structure

~0%

2,2-Dichlorooctane Structure

2,2-Dichlorooctane

2-Chloro-1-octene Structure

2-Chloro-1-octene

2-Octene, 2-chloro Structure

2-Octene, 2-chloro

Detail

2,2-Dichlorooctane Structure

2,2-Dichlorooctane

~7%

2-Octyne Structure

Oct-1-yne Structure

1-Pentylallene Structure

2-Octanone Structure

~%

1-Pentylallene Structure

Regio et stereochimie de la reduction de derives d'alcools p...

[Colas, Yann; Cazes, Bernard; Gore, Jacques Tetrahedron Letters, 1984 , vol. 25, # 8 p. 845 - 848]

Regioselectivity of Intermolecular Pauson–Khand Reaction of ...

[Liu, Yan-Yun; Yang, Xu-Heng; Huang, Xiao-Cheng; Wei, Wen-Ting; Song, Ren-Jie; Li, Jin-Heng Journal of Organic Chemistry, 2013 , vol. 78, # 20 p. 10421 - 10426]

Transformation of nitrimines to acetylenes and allenes. 1, 3...

[Buechi,G.; Wueest,H. Journal of Organic Chemistry, 1979 , vol. 44, p. 4116 - 4120]

Cross??Coupling of Nonactivated Alkyl Halides with Alkynyl G...

[Vechorkin, Oleg; Godinat, Aurelien; Scopelliti, Rosario; Hu, Xile Angewandte Chemie - International Edition, 2011 , vol. 50, # 49 p. 11777 - 11781]

Cross??Coupling of Nonactivated Alkyl Halides with Alkynyl G...

[Vechorkin, Oleg; Godinat, Aurelien; Scopelliti, Rosario; Hu, Xile Angewandte Chemie - International Edition, 2011 , vol. 50, # 49 p. 11777 - 11781]