Tetrahedron letters

Alkylation of ketones by use of solid KOH in dimethyl sulfoxide

E Langhals, H Langhals

Index: Langhals, Elke; Langhals, Heinz Tetrahedron Letters, 1990 , vol. 31, # 6 p. 859 - 862

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Citation Number: 25

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Dedicated to Prof. Dr. Ch. Rüchardt on the occasion of his 60 th birthday. ... A mixture of solid KOH in dimethyl sulfoxide has a strong basicity, but only a low nucleophilicity and is used for methylation of ketones. With this simple and inexpensive reagent complete methylation ...