Photoactivatable HNO-releasing compounds using the retro-Diels–Alder reaction

Y Adachi, H Nakagawa, K Matsuo, T Suzuki…

Index: Adachi, Yusuke; Nakagawa, Hidehiko; Matsuo, Kazuya; Suzuki, Takayoshi; Miyata, Naoki Chemical Communications, 2008 , # 41 p. 5149 - 5151

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Citation Number: 15

Abstract

We synthesized hetero-Diels–Alder cycloadducts from acyl nitroso derivatives and 9, 10- dimethylanthracene, to be photo-inducible HNO-releasing agents and found that introduction of conjugated nitroaromatic groups effectively enhanced the responsiveness of HNO release to UV-A irradiation; we confirmed photoinduced HNO formation by EPR and GCMS analysis.

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