The Hydrogenation of Amides and Ammonium Salts. The Transalkylation of Tertiary Amines

HJ Schneider, H Adkins…

Index: Schneider et al. Journal of the American Chemical Society, 1952 , vol. 74, p. 4287,4288

Full Text: HTML

Citation Number: 13

Abstract

The hydrogenation of certain unsubstituted amides and ammonium salts of acids over copper-chromium-barium oxide (I) has been reinvestigated. Contrary to previous reports, alcohols rather than amines have been isolated as themajor reduction product. The transalkylation of tertiary amines with alcohols, R&+ R'OH--f RzR'N+ ROH, is described. The reaction occurs under hydrogenation conditions over I or Raney nickel catalysts. The ...

Detail

Selective N-alkylation of amines using nitriles under hydrog...

[Ikawa, Takashi; Fujita, Yuki; Mizusaki, Tomoteru; Betsuin, Sae; Takamatsu, Haruki; Maegawa, Tomohiro; Monguchi, Yasunari; Sajiki, Hironao Organic and Biomolecular Chemistry, 2012 , vol. 10, # 2 p. 293 - 304]

Conversion of a (sp 3) C–F bond of alkyl fluorides to (sp 3)...

[Terao, Jun; Begum, Shameem Ara; Shinohara, Yoshiaki; Tomita, Masahiro; Naitoh, Yoshitaka; Kambe, Nobuaki Chemical Communications, 2007 , # 8 p. 855 - 857]

Vinyl-copper derivatives XII: Stereospecific synthesis of al...

[Germon, C.; Alexakis, A.; Normant, J. F. Tetrahedron Letters, 1980 , vol. 21, p. 3763 - 3766]

Cytostatica

[Westphal; Jerchel Chemische Berichte, 1940 , vol. 73, p. 1007]

Reaction of Lithium Diethylamide with an Alkyl Bromide and A...

[Gupta, Lekha; Ramirez, Antonio; Collum, David B. Journal of Organic Chemistry, 2010 , vol. 75, # 24 p. 8392 - 8399]