Zhurnal mikrobiologii, epidemiologii, i immunobiologii 1988-11-01

[The specificity of erythrocyte staphylococcal diagnostic agents in relation to the presence of protein A in sensitin preparations].

P N Deriabin, B V Karal'nik

Index: Zh. Mikrobiol. Epidemiol. Immunobiol. (11) , 85-9, (1988)

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Abstract

Protein A has been detected in Staphylococcus aureus muriatic extracts by means of the passive hemagglutination test and the passive hemagglutination inhibition test with IgG erythrocyte diagnosticum. The absence of perceptible amounts of protein A, capable of interaction with the Fc fragment of IgG, on the surface of erythrocyte diagnosticum obtained from S. aureus muriatic extract with the use of amidol has been proved by different methods. The use of antierythrocytic IgG antibody bridge has shown that protein A in S. aureus muriatic extract is bound with other species-specific antigens, in particular with teichoic acid.