Friedel-Crafts Synthesis of ι-Aroyl Aliphatic Acids1

D Papa, E Schwenk, H Hankin

Index: Papa; Schwenk; Hankin Journal of the American Chemical Society, 1947 , vol. 69, p. 3018,3021

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Citation Number: 38

Abstract

BY DOMENICK PAPA. ERWIN SCHWENK AND HILDA HAIL'KIN w-Aroyl-aliphatic acids have been prepared almost exclusively by Friedel-Crafts reactions between aromatic nuclei and derivatives or anhydrides of dibasic acids. The first general method for the synthesis of these keto acids employed the chlorides of dibasic acids2 as sh. own in equation I. The desired w-aroyl aliphatic: acids