With the aim of improving the cytotoxic and vascular disrupting activities of flavonoids, several classes of ferrocenyl-modified flavonoids were prepared and tested on cancer and endothelial cells. Three ten-member series of ferrocenyl flavonoids: chalcones ((E)-1-(R-2′- hydroxyphenyl)-3-ferrocenylprop-2-en-1-ones), aurones ((Z)-R-2-(ferrocenylidene) benzofuran-3-ones) and flavones (R-2-ferrocenyl-chromen-4-ones) were synthesized by ...
