Tetrahedron

Synthesis and complementary complex formation properties of oligonucleotides covalently linked to new stabilizing agents.

…, E Sottofattori, T Grandi, M Mazzei, TV Abramova…

Index: Balbi; Balbi, Alessandro; Sottofattori; Sottofattori, Enzo; Grandi; Grandi, Teresa; Mazzei; Mazzei, Mauro; Abramova; Abramova, Tatyana V.; Lokhov; Lokhov, Sergej G.; Lebedev; Lebedev, Alexander V. Tetrahedron, 1994 , vol. 50, # 13 p. 4009 - 4018

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Citation Number: 25

Abstract

Oligodeoxyribonucleotides of different lengths have been prepared and linked to new stabilizing agents related to the coumarin family. These ODNSAs ( OligoDeoxyriboNucleotides with Stabilizing Agents) were tested against acridine connected oligomers of the same sequence. Melting temperature experiments demonstrated that all ODNSAs formed complexes of increased stability with complementary sequences of ...