NeuroToxicology 2012-06-01

The similar neurotoxic effects of nanoparticulate and ionic silver in vivo and in vitro

Niels Hadrup, Katrin Loeschner, Alicja Mortensen, Anoop K. Sharma, Klaus Qvortrup, Erik H. Larsen, Henrik R. Lam

Index: Neurotoxicology 33(3) , 416-23, (2012)

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Abstract

Highlights ► Silver ions and silver nanoparticles affect neurotransmitters in rat brain. ► Silver ions and silver nanoparticles induce apoptosis in vitro by both death receptor and mitochondrial pathways. ► Silver ions and 14nm silver nanoparticles seem to have similar neurotoxic mechanisms.