Metal-free oxidative ipso-carboacylation of alkynes: synthesis of 3-acylspiro [4, 5] trienones from n-arylpropiolamides and aldehydes

XH Ouyang, RJ Song, Y Li, B Liu…

Index: Wang, Jing; Liu, Chao; Yuan, Jiwen; Lei, Aiwen New Journal of Chemistry, 2013 , vol. 37, # 6 p. 1700 - 1703

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Citation Number: 29

Abstract

A general and metal-free radical route to synthesis of 3-acylspiro [4, 5] trienones is established that utilizes TBHP (tert-butyl hydrogenperoxide) as an oxidation and a reaction partner to trigger the oxidative ipso-carboacylation of N-arylpropiolamides with aldehydes.