Synthetic communications

Hypervalent Iodine in the Synthesis of Bridgehead Heterocycles: A Facile Route to the Synthesis of 6??Arylimidazo [2, 1??b] thiazoles Using [Hydroxy (tosyloxy) iodo] …

R Aggarwal, G Sumran

Index: Aggarwal, Ranjana; Sumran, Garima Synthetic Communications, 2006 , vol. 36, # 7 p. 875 - 879

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Citation Number: 16

Abstract

Abstract α??Tosyloxyketones (2), readily accessible through hypervalent iodine oxidation of enolizable ketones (1) using [hydroxy (tosyloxy) iodo] benzene (HTIB) in acetonitrile, exclusively generates the 6??arylimidazo [2, 1??b] thiazoles (4) on treatment with commercially available 2??aminothiazole (3).